Both a family saga and the story of one man's struggle to discover his identity, Middlesex tells the story of Calliope Stephanides, or Cal, an intersex man who was raised a girl, only to learn in his teens that he is a male. Due to a history of inbreeding in his family, Cal has a rare genetic condition. He ultimately decides to live as a male, despite having spent years as a female. The conflict between nature and nurture and between choice and fate are major themes in the book.

Summary of Middlesex by Jeffrey Eugenides

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